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Two employees from METR and Redwood Research worked on premises at OpenAI for three weeks this summer in an embedded assessment pilot. This team evaluated the systems OpenAI was using to monitor for misalignment from internal agents. A brief write-up of their work is now public.

GPT-Rosalind surfaced a new lead for drug discovery: could restoring cholesterol transport protect neurons from degeneration? DCTN1 is a gene linked to Perry syndrome, a rare neurodegenerative disorder. In mouse-brain data, disrupting it increased expression of genes involved in making cholesterol. GPT-Rosalind suggested a possible explanation: cholesterol may not be reaching where neurons need it. That gives scientists a specific mechanism to test and, if confirmed, a direction for developing new treatments for neurodegenerative disorders. With @perturbai_tx and @scrippsresearch, a team of thousands of GPT-Rosalind agents worked in parallel, connecting gene-expression results from millions of mouse brain cells with scientific literature in just 32 minutes. We’re now expanding this collaboration to identify new drug targets. https://openai.com/index/scaling-ai-research-for-complex-biological-data/

Introducing Canva Craft 🚀 Extraordinary image generation is now available to everyone, powered by our first frontier model built specifically for design. With Craft, Canva is now the world's second most advanced AI lab for image generation on @DesignArena's global leaderboard. See what it can do 👇

Researchers using GPT-5.6 Sol found massively critical flaw in PHP, which runs about 70% of websites, knocked major sites offline as operators rushed to patch. Calif, an AI security firm, who found this, said in a statement that the vulnerabilities could put 70% of the world’s websites at risk if they aren’t patched quickly, and called them “the most severe vulnerabilities ever discovered by AI, if not in all of software history.” > PHP rushed out fixes as it could let attackers without accounts take over web servers. > Both bugs score 9.2 on the CVSS severity scale and affect PHP versions as old as 5.4. > When a request hits PHP’s memory cap at the wrong moment, PHP frees memory but keeps pointers to it, which a later request on that worker can hijack. > Auditors spotted the weakness in 2024, but the fix stalled for months, partly because nobody had shown a practical attack. > Wiz, a cloud security company, now owned by Google, says the models let one researcher finish in a week what once took a top team months. > A leak of the CVE numbers forced PHP to ship a day early, and Cloudflare now reports early attack attempts.

Introducing 6.1 Sol, near Astra intelligence at one fifth of the price of Astra and 95% cache read discount. It is an absolute workhorse. Combined with ultrafast for 8X speeded available today for Astra and coming soon for 6.1 Sol.